BioWare seems to think so, and so do the various players in the video below. BioWare has released a new trailer for Mass Effect 3, entitled “Better with Kinect”, which highlights the effectiveness of the Kinect-voice controls featured in the game.
I have to admit, the Kinect support appears to work a lot better than I thought it would; I was a bit skeptical when the support was first announced but it appears as if BioWare has found a way to include intuitive controls with the camera and microphone that don’t infringe on the core gameplay. This is the sort of Kinect feature(s) that I could get behind...