Thankfully, I'm not one of them....yet but
some people are experiencing hard freezes of their PlayStation 3 consoles when playing
Uncharted 2. It's not limited to a certain type of console either and so far it seems affect a small percentage of the PS3 population but this might be something to keep on eye on. It doesn't look like it does any damage though so that's good at least but it can happen near the end of the game which just kills the mood a little.
It's not the first time a console from any company had a game cause issues... well has there been one for the Wii? I don't remember a game causing an issue for that one but we've seen reports over the years for some 360 games locking up consoles.